IMMUNE RESPONSE CYTOKINES
Interleukins (ILs): As their name suggests, ILs signal among leukocytes, though cells other than leukocytes may also use interleukins. Immunologists named interleukins sequentially as they were discovered. Currently, scientists have identified about 35 interleukins.
Interferons (IFNs): These antiviral protiens may also act as cytokines. The most important interferon with such a dual function is gamma interferon, which is a potent phagocytic activator secreted by Th1-cells.
Growth Factors: These proteins stimulate leukocyte stem cells to divide, ensuring that the body is supplied with sufficient white blood cells of all types. The body can control the progression of an adaptive immune response by limiting the production of growth factors.
Tumor Necrosis Factor (TNF): Macrophages and T cells secrete TNF to kill tumor cells and to regulate immune responses and inflammation.
Chemokines: Chemokines are chemotactic cytokines; that is, they signal leukocytes to move- for example, to rush to a site of inflammation or infection, or to move within tissues.
No comments:
Post a Comment